What Are The Negative Effects of PrEP? by

What Are The Negative Effects of PrEP?

Posted on Saturday, July 12th, 2014


Gay Star News and other news outlets released the news that the World Health Organization (W.H.O.) announced that all gay and bisexual men who are sexually active should be receiving the treatment known as PrEP. But what about its negative health effects?

Here is the exact wording according to the article:

WHO strongly recommends men who have sex with men consider taking antiretroviral medicines (PrEP) as an additional method of preventing HIV infection alongside the use of condoms. 

However, the article brings up the fact that the health effects of long-term PrEP usage remains unknown. The basic effects of short-term effects are clear:¬†nausea, abdominal cramping, vomiting, dizziness, headache, and fatigue. Long-term consequences aren’t entirely clear but some side-effects are knowledgeable: kidney disease and low bone density, according to The Body Pro.

The Body Pro website presents another angle of perspective on the health consequences of PrEP: they’ll occur anyway. The website analyzes a list of other factors among high-risk groups and list other activities that are threats: smoking, drug use, diabetes, hypertension, cardiovascular disease, and high cholesterol. The medication includes the same toxicity risk as other HIV medication, although a person can have a choice of discontinuing PrEP when they avoid non-monogamous or risky sexual behavior.

Studies have concluded with mixed results. Even according to The Body Pro, another study conducted by Veteran Affairs discovered very little bone loss and kidney risk among people who were taking the same medication as PrEP. This has caused the FDA and CDC to issue a warning to medical practitioners to “avoid PrEP in people with creatinine clearance below 60 mL/min and to consider DEXA scans for candidates with a past fracture or other bone loss risk factors.”

Bottom line: the long-term risks of PrEP medication are present. Perhaps the World Health Organization should consider that aspect before creating a blanket recommendation statement.


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